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Vaksin subunit seperti yang dicontohkan oleh vaksin hepatitis B rekombinan hanya mencakup epitop (bagian spesifik dari antigen yang antibodi atau sel-T mengenali dan mengikat) yang paling mudah merangsang sistem kekebalan tubuh.Berbagai pilihan sumber prediksi di atas sudah terbukti bisa memberikan kemenangan mudah dan bahkan kualitasnya yang sanga
Ketika respon imun berlangsung, sel plasma yang diaktifkan akan mulai memproduksi IgG khusus untuk antigen tertentu. Meskipun IgM adalah antibodi pertama yang diproduksi dan merupakan antibodi yang jauh lebih besar, IgG adalah antibodi penetralisir yang lebih baik. IgG mengikat lebih efektif ke antigen dan membantu dalam opsonisasi. [ 1 ]Upaya awal